Visiting the western Caribbean island of Grand Cayman is a once-in-a-lifetime experience. The best way to do this is by planning a cruise from one of the many Florida ports.
Florida, known as “The Sunshine State,” is also a top-ranked holiday destination in its own right. With so much to do in Florida, it’s worth spending a few days there before or after your cruise. As a sun, sea, and sand location, Florida attracts all kinds of travelers, from partygoers to retirees, nature lovers, thrill seekers, and even foodies, not to mention beachgoers and water sports enthusiasts. Explore some of Florida’s busy, modern cities, quiet beach towns, and beautiful natural areas.
If you’re thinking about taking a cruise from Florida with a stop in Grand Cayman, you have four ports to choose from: Miami, Fort Lauderdale (Port Everglades), Tampa, and Port Canaveral (Orlando). Whichever departure port you choose on your journey from Florida to the West Caribbean island of Grand Cayman, with multiple stops in all kinds of different ports, you’ll be greeted by sandy white beaches, tropical weather, lush green landscapes, and colorful cultures.
So, if you want a vacation that is both exciting and restful, with a layover in Grand Cayman, choose one of the cruises that depart out of Florida.
The Cayman Islands, which are world-renowned for their cuisine, snorkeling, and diving, provide an adventure for individuals of all ages and interests. The majority of them are cruise ship guests who spend a few hours shopping, sunning, or swimming with stingrays before departing. Grand Cayman, the largest of the three, is a popular cruise destination for Western Caribbean cruises, with cruise ships docking in George Town Harbour, which boasts various duty-free shopping choices. Grand Cayman is famous for its beautiful beach, Seven Mile Beach, but it is far from the only attraction. There are numerous activities to choose from, like nightlife and fine dining, kayaking in a bioluminescent bay, spotting blue iguanas, and diving through intricate shipwrecks.
George Town, located on Grand Cayman, is the Cayman Islands’ capital and largest city. Tenders, sometimes known as shuttle boats, carry guests ashore from cruise ships that call at George Town. Passengers disembark in George Town, the heart of Grand[…]
George Town & Grand Cayman Submarine tours of George Town Harbour, glass-bottom boat excursions, snorkeling, scuba diving, parasailing, charter boat trips, rum distillery tours, art galleries, a historical museum, and, of course, shopping and eating are all available to tourists[…]
Find your next cruise to Grand Cayman from Florida’s ports:
7-day cruise to Half Moon Cay, Ocho Rios, George Town and Cozumel on board Nieuw Amsterdam Cruising from: Fort Lauderdale (Port Everglades), Florida; Departure Date: February 9, 2025; Duration: 7-day cruise; Cruise Line: Holland America Line; Cruise Ship: Nieuw Amsterdam; Ports[…]
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6-day cruise to Jamaica, Cayman Islands and Mexico with Carnival Cruises Cruising from: Miami, Florida; Departure Date: February 9, 2025; Duration: 6-day cruise; Cruise Line: Carnival Cruise Line; Cruise Ship: Carnival Horizon; Ports of Call: Miami, Ocho Rios, Grand Cayman, Cozumel,[…]
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6-day cruise to George Town, Cozumel and Bimini with Celebrity Cruises Cruising from: Fort Lauderdale (Port Everglades), Florida; Departure Date: February 9, 2025; Duration: 6-day cruise; Cruise Line: Celebrity Cruises; Cruise Ship: Celebrity Reflection; Ports of Call: Fort Lauderdale, George Town,[…]
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5-day cruise to Jamaica and Grand Cayman with Carnival Cruises Cruising from: Miami, Florida; Departure Date: February 3, 2025; Duration: 5-day cruise; Cruise Line: Carnival Cruise Line; Cruise Ship: Carnival Sunrise; Ports of Call: Miami, Ocho Rios, George Town, Miami; Enjoy[…]
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7-day cruise to Half Moon Cay, Ocho Rios, George Town and Cozumel on board Nieuw Statendam Cruising from: Fort Lauderdale (Port Everglades), Florida; Departure Date: February 1, 2025; Duration: 7-day cruise; Cruise Line: Holland America Line; Cruise Ship: Nieuw Statendam; Ports[…]
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12-day cruise to Cayman Islands, Colombia, Panama, Costa Rica and Mexico with Celebrity Cruises Cruising from: Tampa, Florida; Departure Date: February 1, 2025; Duration: 12-day cruise; Cruise Line: Celebrity Cruises; Cruise Ship: Celebrity Constellation; Ports of Call: Tampa, George Town, Cartagena,[…]
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9-day cruise to Bonaire, Curacao, Aruba and George Town on board Celebrity Cruises Cruising from: Fort Lauderdale (Port Everglades), Florida; Departure Date: January 30, 2025; Duration: 9-day cruise; Cruise Line: Celebrity Cruises; Cruise Ship: Celebrity Eclipse; Ports of Call: Fort Lauderdale,[…]
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6-day cruise to Jamaica, Cayman Islands and Mexico with Carnival Cruises Cruising from: Miami, Florida; Departure Date: January 26, 2025; Duration: 6-day cruise; Cruise Line: Carnival Cruise Line; Cruise Ship: Carnival Horizon; Ports of Call: Miami, Ocho Rios, Grand Cayman, Cozumel,[…]
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6-day cruise to George Town, Cozumel and Bimini with Celebrity Cruises Cruising from: Fort Lauderdale (Port Everglades), Florida; Departure Date: January 26, 2025; Duration: 6-day cruise; Cruise Line: Celebrity Cruises; Cruise Ship: Celebrity Reflection; Ports of Call: Fort Lauderdale, George Town,[…]
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5-day cruise to George Town and Cozumel with Carnival Cruise Line Cruising from: Tampa, Florida; Departure Date: January 20, 2025; Duration: 5-day cruise; Cruise Line: Carnival Cruise Line; Cruise Ship: Carnival Paradise; Ports of Call: Tampa, Grand Cayman, Cozumel, Tampa; Visit[…]
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7-day cruise to Half Moon Cay, Ocho Rios, George Town and Cozumel on board Nieuw Amsterdam Cruising from: Fort Lauderdale (Port Everglades), Florida; Departure Date: January 19, 2025; Duration: 7-day cruise; Cruise Line: Holland America Line; Cruise Ship: Nieuw Amsterdam; Ports[…]
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7-day cruise to Cozumel, George Town, Ocho Rios and Great Stirrup Cay with Norwegian Cruise Line Cruising from: Port Canaveral (Orlando), Florida; Departure Date: January 18, 2025; Duration: 7-day cruise; Cruise Line: Norwegian Cruise Line; Cruise Ship: Norwegian Epic; Ports of[…]
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6-day cruise to Jamaica, Cayman Islands and Mexico with Carnival Cruises Cruising from: Miami, Florida; Departure Date: January 12, 2025; Duration: 6-day cruise; Cruise Line: Carnival Cruise Line; Cruise Ship: Carnival Horizon; Ports of Call: Miami, Ocho Rios, Grand Cayman, Cozumel,[…]
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6-day cruise to George Town, Cozumel and Bimini with Celebrity Cruises Cruising from: Fort Lauderdale (Port Everglades), Florida; Departure Date: January 12, 2025; Duration: 6-day cruise; Cruise Line: Celebrity Cruises; Cruise Ship: Celebrity Reflection; Ports of Call: Fort Lauderdale, George Town,[…]
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7-day cruise to Half Moon Cay, Ocho Rios, George Town and Cozumel on board Nieuw Statendam Cruising from: Fort Lauderdale (Port Everglades), Florida; Departure Date: January 11, 2025; Duration: 7-day cruise; Cruise Line: Holland America Line; Cruise Ship: Nieuw Statendam; Ports[…]
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12-day cruise to Cayman Islands, Colombia, Panama, Costa Rica and Mexico with Celebrity Cruises Cruising from: Tampa, Florida; Departure Date: January 11, 2025; Duration: 12-day cruise; Cruise Line: Celebrity Cruises; Cruise Ship: Celebrity Constellation; Ports of Call: Tampa, George Town, Cartagena,[…]
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5-day cruise to Jamaica and Grand Cayman with Carnival Cruises Cruising from: Miami, Florida; Departure Date: January 6, 2025; Duration: 5-day cruise; Cruise Line: Carnival Cruise Line; Cruise Ship: Carnival Sunrise; Ports of Call: Miami, Ocho Rios, George Town, Miami; Enjoy[…]
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5-day cruise to George Town and Cozumel with Carnival Cruise Line Cruising from: Tampa, Florida; Departure Date: January 6, 2025; Duration: 5-day cruise; Cruise Line: Carnival Cruise Line; Cruise Ship: Carnival Paradise; Ports of Call: Tampa, Grand Cayman, Cozumel, Tampa; Visit[…]
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9-day cruise to Bonaire, Curacao, Aruba and George Town on board Celebrity Cruises Cruising from: Fort Lauderdale (Port Everglades), Florida; Departure Date: January 2, 2025; Duration: 9-day cruise; Cruise Line: Celebrity Cruises; Cruise Ship: Celebrity Eclipse; Ports of Call: Fort Lauderdale,[…]
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7-day Holiday cruise to Half Moon Cay, Ocho Rios, George Town and Cozumel on board Nieuw Amsterdam Cruising from: Fort Lauderdale (Port Everglades), Florida; Departure Date: December 29, 2024; Duration: 7-day cruise; Cruise Line: Holland America Line; Cruise Ship: Nieuw Amsterdam;[…]
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6-day cruise to Jamaica, Cayman Islands and Mexico with Carnival Cruises Cruising from: Miami, Florida; Departure Date: December 29, 2024; Duration: 6-day cruise; Cruise Line: Carnival Cruise Line; Cruise Ship: Carnival Horizon; Ports of Call: Miami, Ocho Rios, Grand Cayman, Cozumel,[…]
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5-day cruise to George Town and Cozumel with Carnival Cruise Line Cruising from: Tampa, Florida; Departure Date: December 23, 2024; Duration: 5-day cruise; Cruise Line: Carnival Cruise Line; Cruise Ship: Carnival Paradise; Ports of Call: Tampa, Grand Cayman, Cozumel, Tampa; Visit[…]
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7-day Holiday cruise to Half Moon Cay, Ocho Rios, George Town and Cozumel on board Nieuw Statendam Cruising from: Fort Lauderdale (Port Everglades), Florida; Departure Date: December 21, 2024; Duration: 7-day cruise; Cruise Line: Holland America Line; Cruise Ship: Nieuw Statendam;[…]
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8-day cruise to Puerto Rico, Panama and Grand Cayman with Carnival Cruise Line Cruising from: Tampa, Florida; Departure Date: December 21, 2024; Duration: 8-day cruise; Cruise Line: Carnival Cruise Line; Cruise Ship: Carnival Legend; Ports of Call: Tampa, Limon, Colon, Panama[…]
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7-day cruise to Cozumel, George Town, Ocho Rios and Great Stirrup Cay with Norwegian Cruise Line Cruising from: Port Canaveral (Orlando), Florida; Departure Date: December 21, 2024; Duration: 7-day cruise; Cruise Line: Norwegian Cruise Line; Cruise Ship: Norwegian Epic; Ports of[…]
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6-day cruise to George Town, Cozumel & Bimini with Celebrity Cruises Cruising from: Fort Lauderdale (Port Everglades), Florida; Departure Date: December 15, 2024; Duration: 6-day cruise; Cruise Line: Celebrity Cruises; Cruise Ship: Celebrity Reflection; Ports of Call: Fort Lauderdale, George Town,[…]
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6-day cruise to Jamaica, Cayman Islands and Mexico with Carnival Cruises Cruising from: Miami, Florida; Departure Date: December 15, 2024; Duration: 6-day cruise; Cruise Line: Carnival Cruise Line; Cruise Ship: Carnival Horizon; Ports of Call: Miami, Ocho Rios, Grand Cayman, Cozumel,[…]
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5-day cruise to Jamaica and Grand Cayman with Carnival Cruises Cruising from: Miami, Florida; Departure Date: December 9, 2024; Duration: 5-day cruise; Cruise Line: Carnival Cruise Line; Cruise Ship: Carnival Sunrise; Ports of Call: Miami, Ocho Rios, George Town, Miami; Enjoy[…]
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5-day cruise to George Town and Cozumel with Carnival Cruise Line Cruising from: Tampa, Florida; Departure Date: December 9, 2024; Duration: 5-day cruise; Cruise Line: Carnival Cruise Line; Cruise Ship: Carnival Paradise; Ports of Call: Tampa, Grand Cayman, Cozumel, Tampa; Visit[…]
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7-day cruise to Half Moon Cay, Ocho Rios, George Town and Cozumel on board Nieuw Amsterdam Cruising from: Fort Lauderdale (Port Everglades), Florida; Departure Date: December 8, 2024; Duration: 7-day cruise; Cruise Line: Holland America Line; Cruise Ship: Nieuw Amsterdam; Ports[…]
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