Cruises to Grand Cayman from Florida

Visiting the western Caribbean island of Grand Cayman is a once-in-a-lifetime experience. The best way to do this is by planning a cruise from one of the many Florida ports.

Florida, known as “The Sunshine State,” is also a top-ranked holiday destination in its own right. With so much to do in Florida, it’s worth spending a few days there before or after your cruise. As a sun, sea, and sand location, Florida attracts all kinds of travelers, from partygoers to retirees, nature lovers, thrill seekers, and even foodies, not to mention beachgoers and water sports enthusiasts. Explore some of Florida’s busy, modern cities, quiet beach towns, and beautiful natural areas.

If you’re thinking about taking a cruise from Florida with a stop in Grand Cayman, you have four ports to choose from: Miami, Fort Lauderdale (Port Everglades), Tampa, and Port Canaveral (Orlando). Whichever departure port you choose on your journey from Florida to the West Caribbean island of Grand Cayman, with multiple stops in all kinds of different ports, you’ll be greeted by sandy white beaches, tropical weather, lush green landscapes, and colorful cultures.

So, if you want a vacation that is both exciting and restful, with a layover in Grand Cayman, choose one of the cruises that depart out of Florida.

Grand Cayman, Cayman Islands

The Cayman Islands, which are world-renowned for their cuisine, snorkeling, and diving, provide an adventure for individuals of all ages and interests. The majority of them are cruise ship guests who spend a few hours shopping, sunning, or swimming with stingrays before departing. Grand Cayman, the largest of the three, is a popular cruise destination for Western Caribbean cruises, with cruise ships docking in George Town Harbour, which boasts various duty-free shopping choices. Grand Cayman is famous for its beautiful beach, Seven Mile Beach, but it is far from the only attraction. There are numerous activities to choose from, like nightlife and fine dining, kayaking in a bioluminescent bay, spotting blue iguanas, and diving through intricate shipwrecks.

George Town

George Town, located on Grand Cayman, is the Cayman Islands’ capital and largest city. Tenders, sometimes known as shuttle boats, carry guests ashore from cruise ships that call at George Town. Passengers disembark in George Town, the heart of Grand[…]

Grand Cayman tourist attractions

George Town & Grand Cayman Submarine tours of George Town Harbour, glass-bottom boat excursions, snorkeling, scuba diving, parasailing, charter boat trips, rum distillery tours, art galleries, a historical museum, and, of course, shopping and eating are all available to tourists[…]

Find your next cruise to Grand Cayman from Florida’s ports:

Carnival Sunrise, Western Caribbean from Miami, March 31, 2025

Carnival Sunrise, Western Caribbean from Miami, March 31, 2025

5-day cruise to Jamaica and Grand Cayman with Carnival Cruises Cruising from: Miami, Florida; Departure Date: March 31, 2025; Duration: 5-day…

1 month ago

Carnival Paradise, Mexico & Grand Cayman from Tampa, March 31, 2025

5-day cruise to George Town and Cozumel with Carnival Cruise Line Cruising from: Tampa, Florida; Departure Date: March 31, 2025;…

1 month ago

Holland America, Western Caribbean from Fort Lauderdale, March 23, 2025

7-day cruise to Half Moon Cay, Ocho Rios, George Town and Cozumel on board Nieuw Amsterdam Cruising from: Fort Lauderdale…

1 month ago

Carnival Horizon, Western Caribbean from Miami, March 23, 2025

6-day cruise to Jamaica, Cayman Islands and Mexico with Carnival Cruises Cruising from: Miami, Florida; Departure Date: March 23, 2025;…

1 month ago

Celebrity Reflection, Western Caribbean from Fort Lauderdale, March 23, 2025

6-day cruise to George Town, Cozumel and Bimini with Celebrity Cruises Cruising from: Fort Lauderdale (Port Everglades), Florida; Departure Date:…

1 month ago

Celebrity Constellation, Western Caribbean from Tampa, March 22, 2025

12-day cruise to Cayman Islands, Colombia, Panama, Costa Rica and Mexico with Celebrity Cruises Cruising from: Tampa, Florida; Departure Date:…

1 month ago

Calebrity Beyond, Panama Canal from Fort Lauderdale, March 17, 2025

11-day cruise to Cartagena, Panama Canal, Colon, Bonaire, Aruba and George Town on board Celebrity Cruises Cruising from: Fort Lauderdale…

2 months ago

Carnival Paradise, Mexico & Grand Cayman from Tampa, March 17, 2025

5-day cruise to George Town and Cozumel with Carnival Cruise Line Cruising from: Tampa, Florida; Departure Date: March 17, 2025;…

2 months ago

Holland America, Western Caribbean from Fort Lauderdale, March 15, 2025

7-day cruise to Half Moon Cay, Ocho Rios, George Town and Cozumel on board Nieuw Statendam Cruising from: Fort Lauderdale…

2 months ago

Norwegian Epic, Western Caribbean from Port Canaveral, March 15, 2025

7-day cruise to Cozumel, George Town, Ocho Rios and Great Stirrup Cay with Norwegian Cruise Line Cruising from: Port Canaveral…

2 months ago

Carnival Horizon, Western Caribbean from Miami, March 9, 2025

6-day cruise to Jamaica, Cayman Islands and Mexico with Carnival Cruises Cruising from: Miami, Florida; Departure Date: March 9, 2025;…

2 months ago

Celebrity Reflection, Western Caribbean from Fort Lauderdale, March 9, 2025

6-day cruise to George Town, Cozumel and Bimini with Celebrity Cruises Cruising from: Fort Lauderdale (Port Everglades), Florida; Departure Date:…

2 months ago

Carnival Sunrise, Western Caribbean from Miami, March 3, 2025

5-day cruise to Jamaica and Grand Cayman with Carnival Cruises Cruising from: Miami, Florida; Departure Date: March 3, 2025; Duration: 5-day…

2 months ago

Carnival Paradise, Mexico & Grand Cayman from Tampa, March 3, 2025

5-day cruise to George Town and Cozumel with Carnival Cruise Line Cruising from: Tampa, Florida; Departure Date: March 3, 2025;…

2 months ago

Celebrity Eclipse, ABC Islands from Fort Lauderdale, February 27, 2025

9-day cruise to Bonaire, Aruba and George Town on board Celebrity Cruises Cruising from: Fort Lauderdale (Port Everglades), Florida; Departure…

2 months ago

Carnival Horizon, Western Caribbean from Miami, February 23, 2025

6-day cruise to Jamaica, Cayman Islands and Mexico with Carnival Cruises Cruising from: Miami, Florida; Departure Date: February 23, 2025;…

2 months ago

Celebrity Reflection, Western Caribbean from Fort Lauderdale, February 23, 2025

6-day cruise to George Town, Cozumel and Bimini with Celebrity Cruises Cruising from: Fort Lauderdale (Port Everglades), Florida; Departure Date:…

2 months ago

Holland America, Western Caribbean from Fort Lauderdale, February 22, 2025

7-day cruise to Half Moon Cay, Ocho Rios, George Town and Cozumel on board Nieuw Statendam Cruising from: Fort Lauderdale…

2 months ago

Carnival Sunrise, Western Caribbean from Miami, February 17, 2025

5-day cruise to Jamaica and Grand Cayman with Carnival Cruises Cruising from: Miami, Florida; Departure Date: February 17, 2025; Duration: 5-day…

3 months ago

Carnival Paradise, Mexico & Grand Cayman from Tampa, February 17, 2025

5-day cruise to George Town and Cozumel with Carnival Cruise Line Cruising from: Tampa, Florida; Departure Date: February 17, 2025;…

3 months ago

Carnival Legend, Panama Canal from Tampa, February 15, 2025

8-day cruise to Puerto Rico, Panama and Grand Cayman with Carnival Cruise Line Cruising from: Tampa, Florida; Departure Date: February…

3 months ago

Norwegian Epic, Western Caribbean from Port Canaveral, February 15, 2025

7-day cruise to Cozumel, George Town, Ocho Rios and Great Stirrup Cay with Norwegian Cruise Line Cruising from: Port Canaveral…

3 months ago

Holland America, Western Caribbean from Fort Lauderdale, February 9, 2025

7-day cruise to Half Moon Cay, Ocho Rios, George Town and Cozumel on board Nieuw Amsterdam Cruising from: Fort Lauderdale…

3 months ago

Carnival Horizon, Western Caribbean from Miami, February 9, 2025

6-day cruise to Jamaica, Cayman Islands and Mexico with Carnival Cruises Cruising from: Miami, Florida; Departure Date: February 9, 2025;…

3 months ago

Celebrity Reflection, Western Caribbean from Fort Lauderdale, February 9, 2025

6-day cruise to George Town, Cozumel and Bimini with Celebrity Cruises Cruising from: Fort Lauderdale (Port Everglades), Florida; Departure Date:…

3 months ago

Carnival Sunrise, Western Caribbean from Miami, February 3, 2025

5-day cruise to Jamaica and Grand Cayman with Carnival Cruises Cruising from: Miami, Florida; Departure Date: February 3, 2025; Duration: 5-day…

3 months ago

Holland America, Western Caribbean from Fort Lauderdale, February 1, 2025

7-day cruise to Half Moon Cay, Ocho Rios, George Town and Cozumel on board Nieuw Statendam Cruising from: Fort Lauderdale…

3 months ago

Celebrity Constellation, Western Caribbean from Tampa, February 1, 2025

12-day cruise to Cayman Islands, Colombia, Panama, Costa Rica and Mexico with Celebrity Cruises Cruising from: Tampa, Florida; Departure Date:…

3 months ago

Celebrity Eclipse, ABC Islands from Fort Lauderdale, January 30, 2025

9-day cruise to Bonaire, Curacao, Aruba and George Town on board Celebrity Cruises Cruising from: Fort Lauderdale (Port Everglades), Florida;…

3 months ago

Carnival Horizon, Western Caribbean from Miami, January 26, 2025

6-day cruise to Jamaica, Cayman Islands and Mexico with Carnival Cruises Cruising from: Miami, Florida; Departure Date: January 26, 2025;…

3 months ago